Migraine May Triple the Risk of Central Serous Chorioretinopathy, Study Finds

By Dr. Kevin -

 A large study found that people who suffer from migraines are almost three times more likely to develop
central serous chorioretinopathy (CSCR), an eye condition that causes fluid buildup under the retina. Researchers analyzed data from over 800,000 adults aged 18–40 and found a CSCR rate of 1.43 per 10,000 in migraine patients, compared with 0.51 per 10,000 in those without migraines. This higher risk was seen across all migraine types and was not affected by common migraine medications.

The findings suggest that migraines and CSCR may share similar vascular causes. Both involve changes in blood flow in the choroid (the eye layer supplying the retina). The study proposes that stress, autonomic nervous system imbalance, and abnormal vascular responses could link the two conditions. Migraine attacks might cause temporary choroidal expansion, and in some people, this may lead to chronic dysfunction and CSCR.

Clinically, the authors recommend that a migraine history be considered a possible risk factor when evaluating CSCR, especially in patients with other vascular conditions, even though corticosteroid use remains the most common trigger.

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