Tuesday, April 14, 2015

THYMOSIN β4 FOR SEVERE DRY EYE

Cornea

Statistically significant differences in both symptom and sign assessments, were seen at various time points throughout the study. Of particular note at day 56, the treated group had 35.1% reduction of ocular discomfort compared with vehicle control, and 59.1% reduction of total corneal fluorescein staining compared with vehicle control. Other improvements seen in the RGN-259–treated patients included tear film breakup time and increased tear volume production.
Conclusions: In this small trial, RGN-259 eye drops were safe and well tolerated and met key efficacy objectives with statistically significant symptom and sign improvements, compared with vehicle control, at various time intervals, including 28-days posttreatment.

FEMTOSECOND LASER FOR IRIDECTOMY-RELATED VISUAL DISTURBANCES

Journal of Glaucoma

Femtolaser assisted keratopigmentation is minimally invasive and results in a significant decrease in the subjective glare and photophobia and even in resolution of monocular diplopia. The cosmetic outcome was also favorable. This technique allows surgeons to correct visual disabilities associated with iris defects with a high success rate while avoiding more aggressive intraocular surgery.