Systemic Medications Associated with Blepharitis, MGD, and Chalazion

By Dr. Kevin -

A recent study found that some systemic medications may contribute to eyelid conditions like blepharitis, meibomian gland dysfunction (MGD), and chalazion. Using FDA adverse event reports (2003–2024), researchers noted higher rates of MGD in patients taking finasteride, chalazia with bortezomib, and all three conditions with dupilumab. Other drugs, such as isotretinoin and certain cancer therapies, were mainly linked to blepharitis. Most patients affected were middle-aged women, with many cases reported in North America.

The authors stress that while these drugs are important for treating serious illnesses, eye side effects should not be ignored. Clinicians should watch for symptoms, educate patients on eyelid hygiene, and include medication history when diagnosing lid inflammation, even if stopping the medication isn’t an option.

Comments

Post a Comment

Leave a Comment or Question:

Popular posts from this blog

IMPLANTABLE COLLAMER LENS APPEARS BETTER THAN LASIK OR PRK FOR MODERATE TO HIGH MYOPIC PATIENTS

By Dr. Kevin -
Image
http://www2.cochrane.org/reviews/en/ab007679.html The results of this review suggest that the implantable lens (ICL) is are safer than excimer laser (the laser used in PRK and LASIK) surgical correction for moderate to high myopia in the range of -6.0 to -20.0 D and ICL is preferred by patients. ICL surgery resulted in better corrected visual acuity, better contrast sensitivity, and improved patient satisfaction. ICL may also be considered in cases where the patient has more moderate near-sightedness (in the range of -3.00 to -6.00). My personal experience with ICL gives me a high level of confidence in this procedure and the surgeon with whom I co-manage. All patients I have seen have been 20/20 or better. One patient was in the -6.00 range and the others in the -10 range! I see very little side effects. For more information, feel free to our office at 480-812-2211.
Read more

RINSING YOUR CONTACT LENS CASE IS NOT ENOUGH

By Dr. Kevin -
Image
Removal of biofilm from contact lens storage cases -- Wu et al., 10.1167/iovs.10-5796 -- Investigative Ophthalmology & Visual Science It has been conventional wisdom amongst eye doctors that most infections related to contact lenses actually originate from the contact lens storage case. I usually recommend rinsing the case after use and filling with fresh solution. However, it appears that thoroughly rubbing the inside of the case with clean fingers helps remove most of the biofilm on which the bacteria grow. I also usually recommend replacing one's case on a regular basis. I am surprised how many new patients come into my office with grimy, dirty contact lens cases. According to this study: "digital rubbing and rinsing, and/or wiping the lens cases with tissue are recommended. Air-drying and recapping the lens case lids after use without any additional cleaning methods or the use of antimicrobial cases should be discouraged."
Read more