DOXYCYCLINE & WARFARIN CAUTION

By Dr. Kevin -
Cornea - Abstract: Cornea, Volume 26(6) July 2007 p 742-743 Interaction of Doxycycline and Warfarin: An Enhanced Anticoagulant Effect.
This paper concludes:

Doxycycline can enhance the anticoagulant effect of warfarin. This is likely due to competitive interaction for albumin binding and possibly inhibition of the cytochrome P-450 system. An increase in plasma levels of free warfarin may result in severe bleeding. It is important to recognize this potential interaction and obtain a complete medication profile prior to initiating doxycycline.

Comments

  1. Anonymous12:16 PM

    The anticoagulant effects of doxycycline can cause complications with medicines like Generic Viagra ?

    ReplyDelete

Post a Comment

Leave a Comment or Question:

Popular posts from this blog

IMPLANTABLE COLLAMER LENS APPEARS BETTER THAN LASIK OR PRK FOR MODERATE TO HIGH MYOPIC PATIENTS

By Dr. Kevin -
Image
http://www2.cochrane.org/reviews/en/ab007679.html The results of this review suggest that the implantable lens (ICL) is are safer than excimer laser (the laser used in PRK and LASIK) surgical correction for moderate to high myopia in the range of -6.0 to -20.0 D and ICL is preferred by patients. ICL surgery resulted in better corrected visual acuity, better contrast sensitivity, and improved patient satisfaction. ICL may also be considered in cases where the patient has more moderate near-sightedness (in the range of -3.00 to -6.00). My personal experience with ICL gives me a high level of confidence in this procedure and the surgeon with whom I co-manage. All patients I have seen have been 20/20 or better. One patient was in the -6.00 range and the others in the -10 range! I see very little side effects. For more information, feel free to our office at 480-812-2211.
Read more

RINSING YOUR CONTACT LENS CASE IS NOT ENOUGH

By Dr. Kevin -
Image
Removal of biofilm from contact lens storage cases -- Wu et al., 10.1167/iovs.10-5796 -- Investigative Ophthalmology & Visual Science It has been conventional wisdom amongst eye doctors that most infections related to contact lenses actually originate from the contact lens storage case. I usually recommend rinsing the case after use and filling with fresh solution. However, it appears that thoroughly rubbing the inside of the case with clean fingers helps remove most of the biofilm on which the bacteria grow. I also usually recommend replacing one's case on a regular basis. I am surprised how many new patients come into my office with grimy, dirty contact lens cases. According to this study: "digital rubbing and rinsing, and/or wiping the lens cases with tissue are recommended. Air-drying and recapping the lens case lids after use without any additional cleaning methods or the use of antimicrobial cases should be discouraged."
Read more

Keratoconus and Inflammatory Skin Conditions

By Dr. Kevin -
Image
 New research shows that keratoconus may be linked to certain inflammatory skin conditions, including eczema (atopic dermatitis), psoriasis, seborrheic dermatitis, contact dermatitis, and hives. People with these conditions were more likely to develop keratoconus than those without them. Rosacea did not show this connection. One possible reason is eye rubbing , which is common in itchy skin conditions and can slowly damage the cornea over time. Another reason may be inflammation in the body , which can weaken collagen—the protein that helps keep the cornea strong and stable. Because of this link, people with chronic inflammatory skin conditions may benefit from earlier and regular eye exams . Controlling inflammation and avoiding eye rubbing may help lower the risk of keratoconus or catch it earlier, when treatment is more effective.
Read more