Monday, June 26, 2006



According to this article:
"More than 100 centers have now reported cases of toxic anterior segment syndrome from February through May 2006...Preoperative use of nonsteroidal anti-inflammatory drugs may be a potential factor..."

...among many other intrasugical factors. TASS results when a noninfectious toxic agent enters the anterior segment during surgery and causes an inflammatory reaction. It is important to differentiate TASS from true infectious endophthalmitis, because the treatments are completely different—and the treatment for one isn’t appropriate for the other.

According to another article in EyeNet:
"if you see limbus-to-limbus corneal edema, a fixed pupil, early onset and high pressure, think TASS."

"If you think it is TASS, give the patient topical prednisolone acetate (Pred Forte) or another powerful topical steroid every hour and a nonsteroidal four times a day. Check IOP daily. Avoid anything that could promote inflammation, such as prostaglandin analogs."

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