This study in the American Journal of Ophthalmology concludes:
In this African ancestry cohort, low BMI was associated with increased POAG risk. POAG cases with low BMI were more likely to have larger cup-to-disc ratios, worse visual acuity, and faster functional progression, indicating more severe glaucoma.
This report on a study demonstrates that there is a slight increase (3% ) in non arteritic ischemic optic neuropathy in patients receiving semiglutide injections. The increase is slightly higher in males than females.
This is a report on a study that suggests that increased vitamin D levels, such as that associated with increased sun exposure, may be correlated with increased risk for macular degeneration.
The researchers found that among patients aged 50 and up, supplement use was associated with lower rates of developing or AMD or progressing AMD when compared with age- and sex-matched patients with no history of supplement use. Tumeric is mentioned in the title of this report.
From Review of Optometry:
Researchers in Taiwan designed a nationwide large study to investigate the association between
Alzheimer's Disease (AD) and different classes of topical glaucoma medications. They determined that using topical alpha-2 adrenergic agonists should be undertaken judiciously, especially in middle-aged and older populations. Their findings also indicated glaucoma may increase the risk of AD regardless of glaucoma subtype.“Our observations indicating that alpha-2 adrenergic agonists potentially confer an increased risk of developing AD when compared to beta-blockers
Irrespective of the type of glaucoma, individuals with glaucoma had a significantly higher risk of AD compared with those without glaucoma.
“Eyecare practitioners and neurologists need to be aware of the potentially higher risk of AD development associated with alpha-2 adrenergic agonists compared with beta-blockers among glaucoma patients,” they concluded in their paper for the journal.
“Good cholesterol” has been praised for its association with reduced cardiovascular disease risk, but new evidence suggests that elevated levels of this high-density lipoprotein cholesterol (HDL-C) may be harmful to the central nervous system. Serum lipid studies have reported associations between HDL-C and increased risk of dementia, and other associations with IOP and glaucoma have also been reported.
the study revealed an association between HDL-C levels and neurodegenerative diseases, suggesting that elevated HDL-C may serve as a novel risk factor for conditions such as dementia."
This report in Review of Optometry demonstrates a relationship between psoriasis and neovascularization in age-related macular degeneration.
According to this study, 1% Atropine administered once per week may be adequate to slow myopia progression. It suggests that some patients may not respond as well, and that this can be determined within the first 2 months of initiation of treatment.
This report discussed this study:
"Each 10mm HG lower in 24-hour average mean arterial pressure and systolic BP were linked with -0.17dB/year and -0.14dB/year faster rates of mean deviation loss. Mean deviation loss was also associated with lower mean systolic BP during follow-up.
"Glaucomatous eyes with progression at low IOP levels may benefit from 24-hour blood pressure monitoring."
Upon analysis, the researchers found that vitamin D supplementation significantly improved tear production by Schirmer testing and tear film stability by tear break-up time and reduced lid hyperemia, and OSDI scores.
The researchers found that 61.1% of patients undergoing the stress test experienced an IOP increase greater than 4mm Hg.
Because of this marked difference, the investigators “believe that repetitive stress stimuli in POAG may compromise IOP control and potentially increase the risk of disease progression.”
On the other side of this trial, some investigations have measured IOP after anti-stress therapies. One of these studies evaluated effects of mindfulness-based stress reduction on IOP and stress biomarkers in a randomized trial. After being assigned either to mindfulness meditation group or control group, results indicated mean IOP reductions from 18.8mm Hg to 12mm Hg in the right eye and 19.0mm Hg to 13.1mm Hg in the left eye of the meditation group.
Taken together, as the authors explain, these correlations “in conjunction with our results, emphasize the correlation between IOP and stress: not only psychological stress can elevate IOP, but anti-stress therapies may improve IOP control.”
According to this study:
"an adverse association between Calcium Channel Blocker (CCB) use and glaucoma was observed, with CCB users having, on average, 39% higher odds of glaucoma. Calcium channel blocker use was also associated with thinner mGCIPL and mRNFL thicknesses, providing a structural basis that supports the association with glaucoma. The lack of association of CCB use with IOP suggests that an IOP-independent mechanism of glaucomatous neurodegeneration may be involved. Although a causal relationship has not been established, CCB replacement or withdrawal may be considered should glaucoma progress despite optimal care."
