A NEW CANDIDATE DRUG FOR NEUROPROTECTIVE TREATMENT IN GLAUCOMA

Investigative Ophthalmology and Visual Science;

Purpose:To investigate the effect of K-115, a novel Rho kinase inhibitor, on retinal ganglion cell (RGC) death in an optic nerve crush (NC) model.  

Conclusions:The results delayed that oral K-115 administration inhibited RGC death...Our findings show that K-115 has a potential use in neuroprotective treatment for glaucoma and other neurodegenerative diseases.