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Wednesday, February 13, 2013

UV-A INHIBITS ACANTHOMOEBAL GROWTH

This study reported in Graefe's Archive for Clinical and Experimental Ophthalmology studied the effect of UV-A exposure, with and without riboflavin, on in vitro acanthomeobal growth.  It's results and were conclusion were:


Results
The exposure of ultraviolet light resulted in an inhibited growth of Acanthamoeba compared to the non-exposed solutions, with a statistically significant reduction over time (p = 0.0003). The addition of riboflavin did not amplify the effect, and there were no tendencies for an interaction effect between UVA and riboflavin.

Conclusions
The antiprotozoal effect of the UVA wavelength, utilized in CXL, is solely mediated by ultraviolet light, and riboflavin does not seem to amplify the antimicrobial efficacy.

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