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Monday, December 03, 2012

COLLAGEN CROSS-LINKING FOR KERATOCONUS

Below is the abstract for the study published in Clinical & Experimental Ophthalmology:


Results

Analysis of the treated group demonstrated a significant flattening of maximum keratometry by 0.96 + 2.33 D (p = 0.005) and a significant improvement in visual acuity by 0.05 + 0.13 logMAR (p = 0.04). In the control group, maximum keratometry increased significantly by 0.43 +0.85 D (p = 0.05) and visual acuity decreased by mean 0.05 + 0.14 (p = 0.2). No statistical differences were noted regarding cylindrical power, spherical equivalent or corneal thickness in both groups.

Conclusions

Results indicate that corneal collagen crosslinking using riboflavin and ultraviolet-A is effective as a therapeutic option in cases of progressive keratoconus by reducing the corneal curvature and improving the visual acuity in these patients.

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