Journal of Clinical Ophthalmology - Dove Medical Press
TBUT was measured in 4,338 patients before switching to or initiating therapy with Optive and at final visit (2 to 4 weeks after treatment initiation). Baseline measurement of mean TBUT was 7.7 ± 3.9 seconds. This value increased to 10.0 ± 4.7 seconds at final visit. Most patients (85.4%) reported improvement in local comfort. The majority (75.1%) of patients felt an improvement in symptoms after changing their treatment.