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Wednesday, December 24, 2008

A NEW NON-STEROID TREATMENT FOR UVEITIS

4115 OLE-OPTH-OA-2008-2(4)-Anglade.pdf

Uveitis is an inflammatory autoimmune disease that affects various parts of the eye and is a leading cause of visual loss. Currently available therapies are burdened with toxicities and/or lack definitive evidence of efficacy. Voclosporin, a rationally designed novel calcineurin inhibitor, exhibits a favorable safety profile and a wide therapeutic window. If successful, voclosporin will become the first Food and Drug Administration-approved corticosteroid-sparing agent for this condition.

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