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Monday, July 09, 2007

DOXYCYCLINE & WARFARIN CAUTION

Cornea - Abstract: Cornea, Volume 26(6) July 2007 p 742-743 Interaction of Doxycycline and Warfarin: An Enhanced Anticoagulant Effect.
This paper concludes:

Doxycycline can enhance the anticoagulant effect of warfarin. This is likely due to competitive interaction for albumin binding and possibly inhibition of the cytochrome P-450 system. An increase in plasma levels of free warfarin may result in severe bleeding. It is important to recognize this potential interaction and obtain a complete medication profile prior to initiating doxycycline.

1 comment:

  1. The anticoagulant effects of doxycycline can cause complications with medicines like Generic Viagra ?

    ReplyDelete

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