“Good cholesterol” has been praised for its association with reduced cardiovascular disease risk, but new evidence suggests that elevated levels of this high-density lipoprotein cholesterol (HDL-C) may be harmful to the central nervous system. Serum lipid studies have reported associations between HDL-C and increased risk of dementia, and other associations with IOP and glaucoma have also been reported.
the study revealed an association between HDL-C levels and neurodegenerative diseases, suggesting that elevated HDL-C may serve as a novel risk factor for conditions such as dementia."